Hey Mark, that's a cool guitar! You would like that.
I'll try not to get too specific in my answer. The short version is you may not need to change pickups, but probably will want to.
This is because Dynasonics (DeArmonds) are some of Gretsch's best pickups according to most people. You have people who love Filtertrons (what TV Jones makes), and you have people who love the DeArmond style pickups. There's no right answer, but a big thing you gotta ask yourself is whether you prefer single coil or humbucker, that's one of the big differences.
Now if you want to get the humbucker, TV Jones style Filtertrons (which is what I personally would do for that guitar), you have your choice of using Magna'Trons, TV Classics, or Power'Trons. I'd go with the Classics or Magna'Trons if you want clarity, or the Power'Trons if you want a harder sound.
Now then, once you choose one of the three pickups (you can call Mr. Jones for more help on that if you want, by the way), you come to choice of mount. Basically, for your use the Dyna'Tron mount is the one you want. Your new pickups will just go under the existing cover you already have.
Actually changing the wiring is tricky though, and unless you're confident with a soldering iron, and extremely patient, I wouldn't try it. It's a hollowbody which makes it infinitely trickier, since there's no plate on the back you unscrew to put electrics in and take them out. You need to solder the entire rig outside, and then feed it in through the F-holes, which can be pretty tricky.
That said, no matter who's doing it, if you've got the money I *highly* recommend buying one of TV's wiring harnesses to go along with the new pickups. You would want this one:
http://www.tvjones.com/cgi-bin/commerce.cgi?preadd=action&key=04-002
The money you spend on the rig is just a little more than what all the components together would cost (they are the best components you can buy), but for the price of labor you actually come ahead (if you're gonna pay somebody else to install this in your guitar).
In short, TV Classics, Dyna'Tron mount, upgrade the electronics, have someone else do the work.
So I hope that answers everything, and isn't confusing! It was a lot of text, sorry about that. Good luck dude!